MEME - Introduction
THE MEME SYSTEM
Multiple EM for Motif Elicitation
Version 3.0
Version 2.2
The MEME system allows you to
discover
motifs (highly conserved regions) in groups of related DNA or protein sequences using
MEME
and,
search
sequence databases using motifs using
MAST
.
The MEME system was developed by
Timothy Bailey
,
Charles Elkan
, and
Bill Grundy
at the
UCSD Computer Science and Engineering
department with input from
Michael Gribskov
at
the San Diego Supercomputer Center
.
MEME is described in detail in the
papers
available here.
You can see
sample MEME output
or
sample MAST output
.
Differences between the current release of the MEME system and earlier releases are described in the
release notes
.
You can download the
ANSI C source code
for the MEME system.
Meta-MEME
combines motif models from MEME into a hidden Markov model framework for use in searching sequence databases.
MEME and MAST are copyrighted software and can be
licensed
for commercial use.